Dear Colleague,

On behalf of the local organizing committee we cordially invite you to participate in the 3rd international Radboudumc Adrenal Masterclass organized by the Radboudumc Center of Expertise for Adrenal Disorders in Nijmegen, the Netherlands. The course will take place on January 14-18, 2019 in Amsterdam, the Netherlands.

We aim to extend the big success of our previous masterclass in January 2017.

The Radboudumc Adrenal Masterclass includes state of the art lectures and workshops on clinical and pathophysiological aspects of adrenal diseases. It serves an audience of adult and pediatric endocrinologists, clinical fellows, internists and clinical chemists who are involved in the management of patients with adrenal disease.

The duration of the masterclass is 5 days, from Monday to Friday. All lectures are given in the English language. Many national and international experts contribute to an intensive program that encompasses all major adrenal disorders: hyper- and hypocortisolism, congenital adrenal hyperplasia, incidentaloma, adrenocortical cancer, pheochromocytoma/ paraganglioma and primary aldosteronism. Apart from overview lectures on theoretical and practical issues, there will be interactive sessions on patient cases with challenging diagnostic and therapeutic issues. Participants are encouraged to present their own cases. Special attention will be paid to indications and interpretation of testing, including imaging procedures. In addition, essential and practical methodological aspects of specific procedures such as adrenal venous sampling and minimally invasive adrenal surgery are demonstrated and discussed.

We very much look forward to meeting you at our third Radboudumc Adrenal Masterclass!

Dr. Henri Timmers (chair)
Dr. Jaap Deinum
Dr. Hedi Claahsen
Dr. Hans Langenhuijsen
  Prof. dr. Jacques Lenders
Prof. dr. Fred Sweep
Prof. dr. Ad Hermus




Title lectures

14-1-2019 12.00 - 12.45    REGISTRATION / CHECK-IN
  12.45 - 13.30 LUNCH  
  13.30 - 13.45 Welcome and Introduction H. Timmers Nijmegen
    Diagnosis of adrenal disease
  13.45 - 14.30 Standardization / harmonisation of modern adrenal hormone assay technology S. Wudy Giessen (Germany)
  14.30 - 15.15 Anatomical imaging of adrenal tumors M. Engelbrecht Amsterdam
  15.00 - 15.30 BREAK  
  15.30 - 16.30 Functional imaging of adrenal tumors Martin Gotthardt Nijmegen
  16.30 - 17.15 Pathology of adrenal tumors R. de Krijger Rotterdam
  18.30 DINNER
Tuesday   Cushing syndrome
15-1-2019 08.30 - 09.30 Pitfalls in diagnosis and differential diagnosis of Cushing's syndrome A. Grossman Oxford (UK)
  09.30 - 10.15 Surgical treatment and assessment of cure after pituitary surgery A. Grotenhuis / A. Hermus Nijmegen
  10.15 - 10.45 Longterm follow-up after successful treatment of Cushing's syndrome S. Roerink Nijmegen
  10.45 - 11.15 BREAK
  11.15 - 12.00 Medical treatment of Cushing's syndrome R. Feelders Rotterdam
  12.00 - 12.45 Case presentations Drs. Yeo Pei Shan, Scheffer-Rath, Van Caenegem, Alkundi  
  12.45 - 13.45 LUNCH
    Adrenal insufficiency
  13.45 - 14.30 Diagnosis and treatment of adrenocortical insufficiency N. Stikkelbroeck Nijmegen
  14.30 - 15.15 Prevention and treatment of Addison crisis A. Hermus Nijmegen
  15.15 - 15.45 BREAK 
  15.45 - 16.30 Adrenal insufficiency in children P. Hindmarsh London (UK)
  16.30 - 17.30 Case presentations Drs. Van Keulen, Smulders, De Fost, Kuenen  
  18.30 DINNER
Wednesday   Primary aldosteronism
16-1-2019 08.30 - 09.15 Differential diagnosis of mineralocorticoid hypertension J. Lenders Nijmegen
  09.15 - 10.00 Tips and tricks in work-up and management of primary aldosteronism J. Deinum Nijmegen
  10.00 - 10.45 Subtyping of primary aldosteronism J. Deinum / L. Schultze Kool Nijmegen
  10.45 - 11.15 BREAK
  11.15 - 12.00 Follow-up of primary aldosteronism M. Reincke Munick (Germany)
  12.00 - 12.45 Case presentations Drs. Jung Soo Lim, Chuah Bingfeng, Stenvers, Wentholt  
  12.45 - 13.45  LUNCH
    Congenital adrenal hyperplasia
  13.45 - 14.30 Basics of steroid synthesis / forms of CAH J. Idkowiak Birmingham (UK)
  14.30 - 15.15 Management of CAH in children H. Claahsen Nijmegen
  15.15 - 15.45 BREAK  
  15.45 - 16.30 Management of CAH in adults N. Stikkelbroeck Nijmegen
  16.30 - 17.30 Case presentations Drs. Bocca (2 cases), Yeo Pei Shan
  18.00 BOAT TRIP and DINNER
Thursday   Pheochromocytoma and paraganglioma
17-1-2019 08.30 - 09.15 Modern biochemical diagnosis of PPGLs J. Lenders Nijmegen
  09.15 - 10.00 Imaging of PPGL anno 2019 H. Timmers Nijmegen
  10.00 - 10.45 Genetic counseling and testing in PPGL F. Hes Leiden
  10.45 - 11.15 BREAK
  11.15 - 12.00 How to prepare patients for adrenal surgery? H. Timmers Nijmegen
  12.00 - 12.45 Case presentations Drs. Canu, Wouters-Van Poppel, Constantinescu  
  12.45 - 13.30 LUNCH
    Patient's perspective
  13.30 - 14.00 A young woman with CAH: more to talk about besides hormones B. Kortmann Nijmegen
  14.00 - 14.30 New approach of care for adrenal patients: AdrenalNET ( J. Beun  
  14.30 - 16.00 Live interviews with patients H. Timmers / J. Deinum / H. Claahsen   Nijmegen
  16.00 FREE TIME
  18.30 DINNER
Friday   Adrenal surgery, incidentaloma and carcinoma
18-1-2019 08.30 - 09.15 Personalized surgery for adrenal patients H. Langenhuijsen Nijmegen
  09.15 - 10.00 Management of incidentaloma M. Kerstens Groningen
  10.00 - 11.45 Dianosis and management of adrenocortical cancer (ACC) G. Assié Paris (France)
  10.45 - 11.15 BREAK
  11.15 - 12.00 Case presentations Drs. Geerdink, Robaczyk (2 cases)  



A certificate of attendance and CME credits will be provided.
Accreditation of this course by the Dutch Society of Internal Medicine is requested.

Location & route

The Masterclass will be given in the Mercure Hotel Amsterdam City in Amsterdam, the Netherlands. It is perfectly located just at the outskirts of the city. It is easily accessible by public transport and even by boat.

Mercure Hotel Amsterdam City
Address: Joan Muyskenweg 10
1096 CJ Amsterdam


Symposium Office: prevents
P.O. Box 73
3480 DB Harmelen
The Netherlands

Maaike Abrahamse
Phone:    +31(6)53 401 561

dr. H.J.L.M. Timmers


Registration is accepted according to the ‘first come, first served’ principle. Participation is only possible for the entire week.

For endocrinologists € 1250 and fellows in training € 995. This includes hotel room and meals.

For those who do not want to stay overnight registration fees are € 750 and € 550 for endocrinologists and fellows in training, respectively.

You will be redirected via this link to the site of, they take care of the registration.

This symposium is organized by bureau-prevents.